NFL Football Week 16 Prediction: San Francisco 49ers vs Seattle Seahawks

by Frank Martin

NFL Football Week 16 Prediction: San Francisco 49ers vs Seattle Seahawks

The San Francisco 49ers can wrap up the NFC West Division title on Sunday but they'll have to end an impressive home streak for the second time in as many weeks to accomplish it. The 49ers will look to pull off an impressive cross-country daily double when they visit the Seattle Seahawks, who still have hopes of overtaking San Francisco for the division crown.

The 49ers ended New England's 21-game December home winning streak with a 41-31 victory last week and now have to take on a Seahawks team that is 6-0 at CenturyLink Field. Seattle has won three straight overall and five of six, and another victory Sunday would pull them within a half-game of San Francisco for the division lead.

  San Francisco 49ers at Seattle Seahawks
When: 8:20 PM ET, Sunday, December 23, 2012
Where: CenturyLink Field, Seattle, Washington
TV: 8:20 p.m. ET, NBC.

Opening Odds: Seattle -1 - O/U: 40½
Current Odds: Seattle -1 - O/U: 39

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San Francisco 49ers (10-3-1): Colin Kaepernick improved to 4-1 as a starter by throwing a career-high four touchdown passes as San Francisco secured a playoff berth against the Patriots. The Niners bolted to a 31-3 lead but had to stave off a stirring comeback after the Patriots reeled off 28 consecutive points to tie the game. Kaepernick responded by throwing his second TD pass to Michael Crabtree, who had seven catches for 107 yards and has 23 receptions over the past three games. San Francisco allowed 520 yards to the Patriots but forced four turnovers and recorded three sacks. The 49ers won a defensive duel with Seattle in Week 7, limiting the Seahawks to 251 yards and getting a season-high 131 yards from Frank Gore in a 13-6 victory.

Seattle Seahawks (9-5): Seattle's offense has erupted in the past two weeks, following a 58-0 beating of Arizona with a 50-17 thrashing of Buffalo to become the first team in 62 years to score 50 points in consecutive weeks. Rookie Russell Wilson was brilliant against the Bills, throwing for 205 yards and a TD and rushing for 92 yards and three scores. Wilson was shut down by the 49ers in the first meeting, throwing for a season-low 122 yards, but he has thrown 11 touchdowns against one interception in his last six games. Running back Marshawn Lynch has gone over 100 yards despite limited duty in each of the past two weeks to give him eight 100-yard games this season, including 103 yards against the Niners.

1. San Francisco has won four straight meetings against the Seahawks, including a 19-17 victory at Seattle on Christmas Eve last season.

2. The 49ers and Seahawks rank 1-2 in the league in fewest points allowed at 15.6 apiece.

3. Gore has the two highest single-game rushing totals in franchise history (212 and 207 yards). Both have come against Seattle.

NFL Football Prediction: 49ers 20, Seahawks 16.

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